Publications by authors named "H Ozgul"
Background And Objectives: Fournier's gangrene (FG) is a polymicrobial-induced necrotizing fasciitis that affects the deep and superficial tissues of the perineal, perianal, scrotal, and genital regions. This study aimed to investigate the role of C-reactive protein (CRP)/lymphocyte and neutrophil/lymphocyte ratios, which are objective markers of inflammatory response, in predicting mortality in patients with FG.
Patients And Methods: Seventy-one patients who underwent surgery for FG between 2019 and 2023 were evaluated retrospectively.
Article Synopsis
- This study aimed to evaluate the prognostic significance of the pan-immune-inflammation value (PIV) in patients with advanced pancreatic cancer, using a sample of 71 patients predominantly treated with the FOLFIRINOX regimen.
- The results showed that high PIV values significantly correlated with increased mortality and poorer survival outcomes, with median overall survival being 9 months for high PIV patients compared to 26 months for those with lower values.
- The findings suggest that PIV can serve as a valuable prognostic biomarker for patient outcomes in advanced pancreatic cancer and highlight the need for further research to confirm these results.
Article Synopsis
- This study evaluated the effectiveness of proton density fat fraction (PDFF) in diagnosing different types of renal tumors using a retrospective analysis of patient data over five years.
- A total of 226 patients with confirmed tumor types underwent multiparametric kidney MRI, measuring fat content in tumors and comparing it with histopathological results.
- Results indicated good diagnostic accuracy with notable differences in mean PDFF values across tumor types, highlighting the potential for PDFF in differentiating between renal tumors.
Effect of ischemia-reperfusion injury on elafin levels in rat liver.
Ulus Travma Acil Cerrahi Derg
February 2024
Article Synopsis
- The study aimed to assess serum elafin levels and its impact on liver injury due to ischemia-reperfusion in rats, comparing multiple groups with varying reperfusion durations after 30 minutes of induced liver ischemia.
- Results indicated a significant decrease in elafin levels as reperfusion time increased, with corresponding increases in ischemia-modified albumin (IMA) and total oxidant status (TOS), highlighting deteriorating liver function.
- Histopathologically, a higher grade of liver injury was associated with lower elafin levels and higher levels of liver enzymes (AST, ALT), indicating a relationship between elafin levels and liver damage severity.
Objective: Anastomotic leakage is a complication that creates significant concern in terms of postoperative morbidity and mortality after colorectal surgery. This study aimed to identify variables for detecting anastomotic leakage in those who had open, laparoscopic, or robotic low anterior resection for cancer and to explore their relationships.
Patients And Methods: A total of 283 patients who were diagnosed with rectal cancer and underwent low anterior resection were divided into two groups: those with and without anastomotic leakage.