Potential profiles of caregivers' benefit finding in ischaemic stroke: The role of personality traits and coping styles.

Objective: To investigate the different categories of benefit finding among caregivers of patients with ischemic stroke and the mechanisms of personality and coping styles using an individual-centered approach.

Methods: A cross-sectional survey was conducted among 235 caregivers of patients with ischemic stroke in the neurology departments of three tertiary hospitals in Bengbu using the revised Inventory of Illness Benefit, the Short Form of the Chinese Big Five Personality Inventory, and the Simplified Coping Style Questionnaire.

Results: The benefit finding of caregivers of patients with ischemic stroke could be categorized into three latent classes: "Low sense of benefit-low personal growth group " (n = 58, 24.

Single-Nucleus and Spatial Transcriptome Profiling Delineates the Multicellular Ecosystem in Hepatocellular Carcinoma After Hepatic Arterial Infusion Chemotherapy.

Hepatic arterial infusion chemotherapy (HAIC) has emerged as a promising treatment strategy for hepatocellular carcinoma (HCC), but a detailed understanding of the multicellular ecosystem after HAIC treatment is lacking. Here, we collected tumor samples from treatment-naïve primary and post-HAIC HCC, and integrated single-nucleus RNA sequencing with spatial transcriptomics to characterize the tumor ecosystem in the post-HAIC HCC. Increased fractions and enhanced cellular communication of CD4 T, CD20 B, and dendritic cell subtypes were identified in post-HAIC tumors.

Nanoparticles-Dotted 3D Porous Nanofiber Skeleton Separator for Advanced Supercapacitors.

As one of the key components of supercapacitors (SCs), separators can directly affect the energy density, output power, and safety stability of SCs. However, it is still a challenge to prepare separators that simultaneously combine large pore size, ultrathin thickness, and excellent mechanical properties. Herein, a 5 μm ultrathin separator with a three-dimensional (3D) porous nanofiber skeleton dotted by fumed AlO nanoparticles has been developed using biaxial stretching.

7-(Diethylamino) coumarin-3-carboxylic acid as a novel antibrowning agent: Activity and mechanism.

Browning caused by polyphenol oxidase (PPO) and microorganisms significantly impacts the nutritional quality of fruits and vegetables. This study identified 7-(Diethylamino) coumarin-3-carboxylic acid (7-DCCA) as an effective inhibitor of both PPO and bacteria. Enzyme assays revealed that 7-DCCA competitively inhibits PPO activity with an IC value of 0.