[Prognosis of 5-year survivors of esophageal cancer treated with radiation and chemotherapy].

Seventeen 5-year survivors, treated with a combination of radiation and chemotherapy, were followed up from 5 to 10 years. Out of them, 10 cases died within 10 years after the completion of radiotherapy. Late local recurrence and remote metastasis of esophageal cancer were observed in 3 cases, and other malignancies of the stomach, lung and esophagus were found in 3 other cases.

[Analysis of 5-year survivors of esophageal cancer treated with radiation and chemotherapy].

From 1967 to 1980, 240 cases of esophageal cancer, consisting of 153 curative and 87 palliative cases, were treated with a combination of radiation and chemotherapy. The five-year survival rate in 124 curative cases given a dose of more than 50 Gy was 12.9%, and 17 cases survived more than 5 years.

[Evaluation of combined radiotherapy of gastric carcinoma].

Combined radiotherapy with chemotherapy was performed on 82 patients with advanced gastric carcinoma (T2-T4: M0). A small target volume, including the primary lesion and regional lymph nodes (N1), was irradiated with the dose of 60 Gy. The survival rate was 21% at two years and 6% at five.

Radiation therapy of carcinoma in the rectum and sigmoid colon.

Radiation therapy combined with some anti-cancer drugs was performed in a total of 79 patients with carcinoma of the rectum and sigmoid colon, consisting of 41 primary, 25 recurrent and 13 postoperatively irradiated ones. Relief of subjective symptoms was observed in 50% or more of primary and recurrent patients. Radiation response of tumor was marked in 23 (56%) of primary ones.

[Treatment of operable breast cancer by tumorectomy and irradiation].

Six patients with operable breast cancer were treated by tumorectomy followed by radiotherapy at Miyagi Seijinbyo Center between 1972 and 1982. All patients are alive but local recurrence at the irradiated breast and lung metastasis occurred in one patient each. Acute skin reaction was evident in two patients and slight fibrosis of the irradiated breast was observed in another patient.