Publications by authors named "H Ohtsu"

Standard trastuzumab therapy can reduce the risk of early recurrence of HER2-positive breast cancer. However, trastuzumab-induced cardiac dysfunction may force the discontinuation of adjuvant trastuzumab therapy. Incidentally, there are still unclear whether or not trastuzumab treatment should be continued in the setting of reduced cardiac function.

View Article and Find Full Text PDF
Article Synopsis
  • The study involved 20 Boris brown laying hens, with one group exposed to prolonged heat (32°C) while the other group was kept at a stable temperature (24°C).
  • Results showed that chronic heat exposure led to increased levels of IS, activated certain genes related to stress and fibrosis, and harmed the antioxidant capacity of the kidneys, suggesting that IS accumulation contributes to kidney damage in laying hens.
View Article and Find Full Text PDF
Article Synopsis
  • - The study aims to evaluate the effectiveness of injecting autologous concentrated bone marrow into the healthy femoral head in patients with bilateral osteonecrosis of the femoral head, while one side undergoes total hip arthroplasty (THA) due to collapse.
  • - It is a multicenter, prospective study that will monitor femoral head collapse through X-rays and assess patient outcomes such as safety, pain, and hip function over a period of two years.
  • - The research protocol has been ethically approved and will follow regulatory standards in Japan, with plans to publish the findings in a peer-reviewed journal.
View Article and Find Full Text PDF

Aims: The utilization of long-term effect of internet of things (IoT) on glycemic control is controversial. This trial aimed to examine the effect of an IoT-based approach for type 2 diabetes.

Materials And Methods: This randomized controlled trial enrolled 1,159 adults aged 20-74 years with type 2 diabetes with a HbA1c of 6.

View Article and Find Full Text PDF

Highly luminescent silver(I) coordination polymers [AgX(PPh)(Mepyz)] (X = I, Br, Cl; Mepyz: 2,5-dimethylpyrazine) were prepared together with copper congeners [CuX(PPh)(Mepyz)] (X = I, Br). All the complexes showed thermally activated delayed fluorescence from the charge-transfer states in the visible region, from blue to red. The isomorphous relationship among the complexes allowed a detailed discussion of the effect of halogenido ligands and crystal packing on their luminescence energy.

View Article and Find Full Text PDF