Prevalence of premenstrual syndrome in autism: a prospective observer-rated study.

A systematic, prospective observer-rated study was carried out to determine the prevalence of late luteal phase dysphoric disorder (premenstrual syndrome) in women with autism. A group of women with autism and learning disability (n = 26) was compared with a group of women with a non-autism learning disability (n = 36) matched for age, in-patient status, intelligence, marital status, parity, behavioural problems and ethnicity. Observers rated DSM-IV symptoms of late luteal phase dysphoric disorder every day from each subject over three consecutive menstrual cycles.

Changes in the use of EEG following clinical audit.

An audit of the clinical use of EEG in mentally handicapped patients was performed over a three-year period. EEG requests seemed inappropriate in more than one-quarter of cases. Changes in clinical practice during the 10 months following presentation of these audit results were examined.

A comparison of prescribed medication in learning disability patients before and after resettlement from hospital into the community.

The use of prescribed medication was examined in 34 people with learning disability who underwent a planned resettlement from a hospital into the community. No significant differences were found in the number of subjects receiving antipsychotic, antimuscarinic, antidepressant, and anticonvulsant medication, lithium preparations, and non-psychoactive medication, just prior to discharge and 1 year after discharge. This study indicates that long-stay hospitalised adults with moderate, severe or profound mental retardation can successfully be relocated into the community--in spite of suffering from behavioural and major psychiatric disorders--with the aid of appropriate medication, psychiatric follow-up, and community resources.

Kallmann's syndrome and mental handicap.

A case of Kallmann's syndrome is reported in a 62-year-old mentally handicapped man with clinical and laboratory characteristics of the syndrome. The literature is reviewed and the possible associations with mental handicap explored.