Publications by authors named "H O Zender"

Tumor lysis syndrome is a metabolic emergency resulting from a massive destruction of cancer cells. This is often associated with hematological malignancies, such as non-Hodgkin's lymphoma and acute leukemia, but the incidence tends to increase for solid tumors with the development of oncological treatments. Due to a poor prognosis, it is essential to recognize this syndrome early.

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Article Synopsis
  • Most causes of delirium are not neurological, making neurological diagnostic tests (NDTs) potentially less effective in diagnosing it.
  • A study evaluated patients in an internal medicine ward to assess the relationship between delirium and the use of NDTs, finding that those with delirium were more likely to undergo these tests but received minimal actionable results.
  • The findings suggest that while patients with delirium had more NDTs, these tests had a low impact on treatment decisions, highlighting the need for better guidelines to manage delirium cases.
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Abiraterone acetate is a steroidal inhibitor of cytochrome P450 17A1 indicated in the treatment of metastatic prostate cancer. This report examines the case of a 66-year-old patient diagnosed with prostate adenocarcinoma that had metastasized to the bones and lymph nodes. Treatment with abiraterone acetate and corticosteroid co-administration as well as LH-RH analog hormone therapy was initiated.

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Post-Obstructive Diuresis (POD) is a polyuria that occurs following the release of an obstruction from the urinary tract that prevents the flow of urine. POD requires prompt diagnosis to avoid complications. Although its pathophysiology is better understood, there is little scientific evidence for its treatment.

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Between mid-October 2020 and mid-January 2021, during the second wave of COVID-19 pandemia, 125 patients have been admitted in the intensive care units of Neuchâtel network hospitals. To manage this flow, the bed capacity of intensive care unit increased by 240%. Each patient received corticosteroids, an increased prophylactic anticoagulation and an antibiotic.

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