Publications by authors named "H O Olawumi"

Genomic profiles and prognostic biomarkers in patients with acute myeloid leukemia (AML) from ancestry-diverse populations are underexplored. We analyzed the exomes and transcriptomes of 100 patients with AML with genomically confirmed African ancestry (Black; Alliance) and compared their somatic mutation frequencies with those of 323 self-reported white patients with AML, 55% of whom had genomically confirmed European ancestry (white; BeatAML). Here we find that 73% of 162 gene mutations recurrent in Black patients, including a hitherto unreported PHIP alteration detected in 7% of patients, were found in one white patient or not detected.

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Article Synopsis
  • The study assessed the lipid profiles and atherogenic risk indices of 45 Nigerian breast cancer patients compared to 50 normal control subjects.
  • The results indicated that breast cancer patients had significantly higher triglycerides and atherogenic indices while having lower HDL cholesterol levels than the control group.
  • Overall, the findings highlight that breast cancer patients in Nigeria exhibit a higher prevalence of dyslipidemia and cardiovascular risk compared to the general population.
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Objective: This cross-sectional study was conducted on the associations between body composition, energy expenditure and caloric intake among 45 Nigerian breast cancer patients.

Methods: Forty-five Nigerian breast cancer patients were measured and analysed for their body composition, energy expenditure and caloric intake. Statistical analyses included a chi-square test, Student's -test, paired -test, Spearman correlation and linear regression using Statistical Package for the Social Sciences 23.

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Background And Objectives: Women are grossly under-represented among blood donors in Nigeria. We, therefore, determined the barriers, motivators and appealing incentives to blood donation among women in Nigeria.

Materials And Methods: This was an internet-based cross-sectional study among women aged 18-65 years.

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Background: Functional iron deficiency has been found to be a common cause of poor response to erythropoiesis stimulating agents in anaemic patients with chronic kidney disease (CKD).

Objectives: Assess the functional iron status of patients with chronic kidney disease.

Methods: This was a hospital based cross sectional study.

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