Publications by authors named "H Numminen"
Article Synopsis
- The study examined the link between heavy alcohol use and young-onset cryptogenic ischemic stroke (CIS) in individuals aged 18-49.
- Patients showed significantly higher rates of heavy drinking compared to stroke-free controls, with 13.7% of CIS patients classified as heavy alcohol users versus 6.7% of controls.
- The findings suggest that heavy alcohol consumption, especially binge drinking, is an independent risk factor for CIS in young men, but not in women.
Background: The influence of burden of atherosclerosis in the brain supplying arteries on mortality in patients with acute ischemic stroke or transient ischemic attack is poorly known. We assessed whether total burden of atherosclerosis within cervicocerebral arteries is associated with long-term mortality.
Methods And Results: A total of 406 patients (median age, 71.
Article Synopsis
- Up to 40% of ischemic strokes in young patients are cryptogenic, leading to a study comparing blood pressure profiles between these patients and stroke-free controls.
- The study involved 132 young patients with cryptogenic ischemic strokes and 106 controls, assessing 24-hour ambulatory blood pressure patterns, including day/night variations.
- Results indicated that non-dipping patterns of diastolic blood pressure were linked to cryptogenic ischemic strokes, particularly in patients without a patent foramen ovale, suggesting different underlying causes for strokes in patients with and without this condition.
Article Synopsis
- - The study investigated the link between obesity and early-onset cryptogenic ischemic stroke (CIS) in young adults, focusing on how fat distribution and gender might influence this relationship.
- - In a sample of 345 young patients with acute CIS and an equal number of stroke-free controls, the research found a significant association between higher waist-to-hip ratios (WHR) and the risk of CIS, particularly in women.
- - Results indicated that while WHR was a strong independent risk factor for CIS in young adults, other obesity measures like body mass index (BMI) and waist circumference did not show a similar association after controlling for various factors.
Backround: Venous thromboembolism (VTE) after primary intracerebral hemorrhage (ICH) worsens patient prognosis. Administering low-molecular weight heparins (LMWH) to prevent VTE early (24 h) may increase the risk of hematoma enlargement, whereas administering late (72 h) after onset may decrease its effect on VTE prevention. The authors investigated when it is safe and effective to start LMWH in ICH patients.
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