Publications by authors named "H Nonogi"
Aim: The optimal timing of adrenaline administration after defibrillation in patients with out-of-hospital cardiac arrest (OHCA) and an initial shockable rhythm is unknown. We investigated the association between the defibrillation-to-adrenaline interval and clinical outcomes.
Methods: Between 2011 and 2020, we enrolled 1,259,960 patients with OHCA into a nationwide prospective population-based registry in Japan.
Background: International consensus on cardiopulmonary resuscitation (CPR) and emergency cardiovascular care science and treatment recommendations (CoSTR) have reported updates on CPR maneuvers every 5 years since 2000. However, few national population-based studies have investigated the comprehensive effectiveness of those updates for out-of-hospital cardiac arrest due to shockable rhythms. The primary objective of the present study was to determine whether CPR based on CoSTR 2005 or 2010 was associated with improved outcomes in Japan, as compared with CPR based on Guidelines 2000.
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- Defibrillation is key in improving survival rates and spontaneous circulation in out-of-hospital cardiac arrest cases with shockable rhythms, and prehospital adrenaline can boost the chances of early recovery.
- A study analyzed over 1.8 million OHCA cases in Japan, focusing on 81,056 patients with witnessed cardiac arrest and a shockable rhythm, to assess how the number of defibrillation attempts influenced survival and neurological outcomes.
- While more defibrillation attempts generally led to lower neurological survival rates for most, the trend flipped for patients given adrenaline, where up to four shocks improved outcomes.