Publications by authors named "H Nollet"

Reasons For Performing Study: Transcranial magnetic stimulation (TMS) is an electrophysiological technique used to elicit motor evoked potentials (MMEPs) to evaluate the functional integrity of the descending motor fibres in the spinal cord. Successful application of the technique was reported in horses with spinal cord compression. However, limited data are available on the correlation of TMS with histopathological changes.

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Bovine eosinophilic myositis (BEM) is a subclinical myopathy characterized by multifocal white to grey-green discolorations in skeletal muscles, heart, tongue and oesophagus. These lesions are found at slaughter or during meat cutting and result in considerable economic losses. The etiology and pathogenesis are unclear, although it has been suggested, that Sarcocystis species are involved.

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The aim of this study was to assess the feasibility of implanting an existing vagus nerve stimulating (VNS) electrode around the recurrent laryngeal nerve. The stimulus response characteristics required to achieve abduction of the ipsilateral arytenoid by the VNS electrode in the normal horse could then be determined. The electrode was wound around the left recurrent laryngeal nerve at the cervical level and connected to a pulse generator.

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Case Description: An 8-year-old warmblood mare was evaluated following an acute onset of neurologic abnormalities.

Clinical Findings: Computed tomography of the head revealed large masses in both lateral ventricles, and a presumptive diagnosis of cholesterinic granuloma was made.

Treatment And Outcome: Freehand biopsy of the intracranial masses was performed under computed tomographic guidance, and histologic examination of biopsy specimens confirmed the diagnosis.

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Article Synopsis
  • The study examined the relationship between onset latency and peak-to-peak amplitude of magnetic motor evoked potentials (MMEP) in dogs subjected to transcranial magnetic stimulation (TMS) under various sedative and hypnotic drug combinations.
  • Data for bispectral analysis index (BIS) and autoregressive model-derived auditory evoked potential index (AAI) were collected, but their fluctuations were not significantly related to the MMEP changes.
  • Conclusively, the findings suggest that BIS and AAI are not effective methods for adjusting sedation and anesthesia in dogs during TMS procedures.
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