Publications by authors named "H Nikki March"

Objective: To understand the sociotechnical factors affecting medication safety when intensive care patients are transferred to a hospital ward. Consideration of these medication safety factors would provide a theoretical basis, on which future interventions can be developed and evaluated to improve patient care.

Design: Qualitative study using semistructured interviews of intensive care and hospital ward-based healthcare professionals.

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The final effect of pesticides and their mixtures on living organisms is determined by the particular toxicodynamics of the system. Oxidative stress is one of the most studied molecular mechanisms of toxicity due to increasing evidence supporting its association with the toxic effects of different agrochemicals. In the present study we evaluated the presence of redox balance alterations in the cell lines HEp-2 and A549 exposed to formulations of glyphosate (March®) and cypermethrin (Superfina®) used separately or in combination (in a proportion equivalent to that used in soybean fields).

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Planetary Health has emerged as a new approach to respond to the existential risks that the clime and global environmental crises pose to human societies. As stated by various stakeholders, the challenges involved in Planetary Health are of such magnitude that education must be at the forefront to obtain a meaningful response. Universities and higher education institutions have been specifically called to embed the concept of planetary stewardship in all curricula and train the next generation of researchers and change makers as a matter of urgency.

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Article Synopsis
  • * Traditional quantitative PCR is the primary method for qNAATs, but there's a push for developing simpler, point-of-care (POC) solutions suitable for various settings, especially in low-resource areas.
  • * This study introduces a new method using recombinase polymerase amplification (RPA) on paper membranes, allowing for rapid quantification of HIV nucleic acids in under 20 minutes, with a mobile phone system that captures and processes images to analyze results.
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Article Synopsis
  • Quantitative nucleic acid amplification tests (qNAATs) are essential for monitoring viral loads in infections like HIV and SARS-CoV-2, where viral load indicates disease status.
  • * Traditional quantitative PCR is the standard method, but there's a push for point-of-care (POC) qNAATs, especially in outpatient clinics and lower-resource settings.
  • * This study introduces a new method using recombinase polymerase amplification (RPA) on paper membranes, allowing for rapid quantification of HIV-1 DNA and RNA in under 20 minutes, with a mobile phone system for image capture and processing.
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