1 GW peak power and 100 J pulsed operation of a diode-pumped Tm:YLF laser.

We report on the generation of high energy, high power pulses in a tabletop diode-pumped Tm:YLF-based laser system, which delivers amplified pulse energies up to 108 J, as well as GW peak power performance when seeded with nanosecond duration pulses. Furthermore, the high power and efficiency capabilities of operating Tm:YLF in the multi-pulse extraction (MPE) regime were explored by seeding the experimental setup with a multi-kHz burst of pulses exhibiting a low individual pulse fluence, resulting in a 3.6 kW average power train of multi-joule-level pulses with an optical-to-optical efficiency of 19%.

Demonstration of a compact, multi-joule, diode-pumped Tm:YLF laser.

We report the demonstration of a diode-pumped Tm:YLF laser operating at 1.88 µm that produces pulse energies up to 3.88 J in 20 ns.

New synthetic opioid cyclopropylfentanyl together with other novel synthetic opioids in respiratory insufficient comatose patients detected by toxicological analysis.

: Fentanyl derivatives like cyclopropylfentanyl have recently appeared on the recreational drug market. Cyclopropylfentanyl is probably a highly potent opioid, but human toxicological data are not available so far. Similar to other fentanyl derivatives the most serious acute health risk due to the use of cyclopropylfentanyl is likely to be respiratory depression.

Direct assessment of adherence and drug interactions in patients with hypertensive crisis-A cross-sectional study in the Emergency Department.

Though drug adherence is supposed to be low in hypertensive crisis (HTN-C), there are no data available from direct adherence assessments. The aim of the present study was to evaluate adherence to prescribed antihypertensives and potential interactions of concomitant drugs and foods with prescribed antihypertensives in patients with HTN-C by a direct evaluation via biochemical urine analysis. In the present cross-sectional study, 100 patients with HTN-C, admitted to the emergency department (ED), were included.

INVESTIGATIONS INTO CAUSES OF NEUROLOGIC SIGNS AND MORTALITY AND THE FIRST IDENTIFICATION OF SARCOCYSTIS CALCHASI IN FREE-RANGING WOODPECKERS IN GERMANY.

Between June and November 2015, 25 woodpeckers (Picidae) with neurologic signs or unknown cause of death were admitted to a veterinary clinic. Alive birds were clinically examined. Birds that were found dead or died despite intensive care treatment were forwarded to a pathologic examination.