Publications by authors named "H Nebelung"
Background: Microvascular invasion is a major histopathological risk factor of postoperative recurrence in patients with hepatocellular carcinoma. This study aimed to develop and validate a digital biopsy model using imaging features to predict microvascular invasion before hepatectomy.
Methods: A total of 217 consecutive patients who underwent hepatectomy for resectable hepatocellular carcinoma were enrolled at two tertiary-care reference centers.
Objectives: To determine the feasibility and diagnostic accuracy of fast whole-body magnetic resonance imaging (WB-MRI) compared to whole-body computed tomography (WB-CT) in detecting injuries of slightly to moderately injured trauma patients.
Materials And Methods: In a prospective single-center approach, trauma patients from convenience sampling with an expected Abbreviated Injury Scale (AIS) score ≤ 3 at admission, received an indicated contrast-enhanced WB-CT (reference standard) and a plain WB-MRI (index test) voluntarily up to five days after trauma. Two radiologists, blinded to the WB-CT findings, evaluated the absence or presence of injuries with WB-MRI in four body regions: head, torso, axial skeleton, and upper extremity.
[Radiologically guided interventional therapies for the treatment of neuroendocrine tumors].
Radiologie (Heidelb)
July 2024
Background: The majority of patients with neuroendocrine tumors (NET) develop liver metastases during the course of the disease, significantly impacting prognosis and quality of life.
Clinical Issue: Radiologically guided interventional therapies, such as thermal ablation, transarterial embolization (TAE)/chemoembolization (TACE), and selective internal radiotherapy (TARE), can play a crucial role in the treatment of metastatic NET.
Data: Due to the rarity of the disease, the majority of evidence is based on retrospective studies.
To examine the comparative robustness of computed tomography (CT)-based conventional radiomics and deep-learning convolutional neural networks (CNN) to predict overall survival (OS) in HCC patients. Retrospectively, 114 HCC patients with pretherapeutic CT of the liver were randomized into a development (n = 85) and a validation (n = 29) cohort, including patients of all tumor stages and several applied therapies. In addition to clinical parameters, image annotations of the liver parenchyma and of tumor findings on CT were available.
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- Aortic intramural hematoma (IMH) is a rare condition, and this study aimed to analyze its clinical presentation, treatment approaches, and outcomes in type B cases over a nine-year period.
- The study included 35 patients, primarily presenting with back pain, and compared the effectiveness of conservative treatment to endovascular approaches (TEVAR), finding both methods led to a reduction in hematoma thickness.
- Results indicate a generally favorable prognosis for IMH patients, although those with ulcer-like projections (ULPs) required more attention due to increased risks of complications and poorer remodeling outcomes.