Association of salivary proteins with dental caries in children with mixed dentition: a systematic review.

Purpose: To review the current evidence on the association between salivary protein profile and dental caries in children during mixed dentition stage.

Methods: This systematic review followed the PRISMA 2020 guidelines. Searches were run in PubMed, Scopus and Embase along with gray literature.

Content of cariostatic trace elements (F, Cu, and Zn) in the commercially packaged and public tap waters of Qatar.

Objectives: Drinking water containing optimal levels of cariostatic trace elements is an effective preventive approach against community-wide dental caries. This study aimed to (i) determine the concentrations of fluoride, copper, and zinc in commercially packaged and public tap water available in Qatar, (ii) assess the accuracy of the content of these cariostatic trace elements on commercial water brand labels, and (iii) check for seasonal fluctuations in the levels of these trace elements in commercial and public water samples.

Methods: Duplicate samples from 20 commercial and six public tap water sources were collected once in the summer and winter seasons.

A Facile Synthesis of Red-Shifted Bis-Quinoline (BisQ) Surrogate Base.

Forced intercalation peptide nucleic acids (FIT-PNAs) are DNA mimics that act as RNA sensors. The sensing event occurs due to sequence-specific RNA hybridization, leading to a substantial increase in fluorescence. The fluorophore in the FIT-PNA is termed a surrogate base.

Detecting the lncRNA in Ovarian Cancer with Cyclopentane-Modified FIT-PNAs (cpFIT-PNAs).

Ovarian cancer (OC) is one of the most lethal gynecologic cancers that is typically diagnosed at the very late stage of disease progression. Thus, there is an unmet need to develop diagnostic probes for early detection of OC. One approach may rely on RNA as a molecular biomarker.