Publications by authors named "H Nazarian"
Article Synopsis
- The study investigates how photobiomodulation (PBM) affects the testis of prepubertal male mice exposed to heat stress, which is known to damage testicular health.
- Twenty-four male mice were divided into three groups: a control group, a hyperthermia group, and a hyperthermia plus PBM group, where heat was applied to induce stress and laser therapy was used to assess its protective effects.
- Results showed that the PBM treatment improved sperm quality, increased testicular cell counts, boosted testosterone levels, and reduced harmful oxidative stress, suggesting that laser therapy can help protect the testis from heat damage during critical developmental periods.
Article Synopsis
- Unhealthy lifestyle choices like alcohol, chemicals, and heat stress can negatively impact male fertility by damaging the blood-testis barrier (BTB), which is crucial for sperm production.
- Recent studies have explored photobiomodulation therapy (PBMT) as a way to improve sperm quality, particularly in cases with genital inflammation.
- In an experiment with male mice subjected to heat stress, PBMT was found to significantly enhance sperm quality and the health of the BTB, offering a promising method for treating male infertility.
Prostate cancer (PC) is a leading cause of cancer-related mortality in men worldwide, and identifying key molecular players in its pathogenesis is essential for advancing effective diagnosis and therapy. MicroRNAs (miRNAs) have recently emerged as significant molecules involved in the progression of various cancers. As noncoding RNAs, miRNAs play a vital role in regulating gene expression and are implicated in several aspects of cancer pathogenesis.
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- - The study investigates the effects of phenanthrene, a harmful environmental pollutant, on testicular tissue and Sertoli cell function in male F1 mice following maternal exposure during pregnancy.
- - Female rats were divided into three groups (control, sham, and phenanthrene) and offspring were analyzed at 56 days postnatal, revealing detrimental changes in testicular structure and function due to phenanthrene exposure.
- - Findings indicate that maternal phenanthrene exposure leads to lower testicular weight, increased cell death, and reduced Sertoli cell function, potentially resulting in fertility issues for male offspring.