Publications by authors named "H Nassereddine"

Bullous pemphigoid (BP) is the most prevalent autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and manifests with pruritus and localized or, most commonly, generalized bullous lesions. Numerous studies have established the association between BP and oral antidiabetic agents, particularly dipeptidyl peptidase 4 (DPP4) inhibitors, diuretics, and certain antibiotics, notably levofloxacin and cephalexin.

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Background: We present this case to highlight the importance of considering seromucinous hamartoma in the differential diagnosis of nasal cavity lesions, particularly due to its rarity and potential for being mistaken for more aggressive pathologies. Seromucinous hamartoma, although benign, can exhibit clinical and histological features that overlap with those of malignant tumors, posing a diagnostic challenge. This case is especially noteworthy due to the unusual presentation of sebaceous differentiation within seromucinous hamartoma, a feature not previously documented in the literature.

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Article Synopsis
  • Thiamine deficiency is observed in patients with acute illnesses, regardless of alcohol use disorder, particularly in those with sepsis, diabetic ketoacidosis, and oncologic emergencies.
  • A study of 269 emergency department patients revealed that 20.5% had thiamine deficiency, with significant associations found for age over 60, female gender, leukopenia, moderate anemia, and hypoalbuminemia.
  • The findings suggest that older age, being female, and having low white blood cell counts are key factors linked to thiamine deficiency in critically ill patients.
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  • The study evaluates the economic impact of an accelerated protocol (AP) for diagnosing myocardial infarction (MI) using high-sensitivity cardiac troponin (hs-cTn) compared to conventional testing methods.
  • Conducted across nine emergency departments, the research analyzed costs and length of stay for nearly 32,450 patients suspected of having MI.
  • Results showed that the AP did not significantly increase treatment costs or length of stay overall, but some lower acuity emergency departments experienced shorter stays and lower health system costs with the AP.
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