Publications by authors named "H Nan"
Background: Investigating brain metabolic networks is crucial for understanding the pathogenesis and functional alterations in Creutzfeldt-Jakob disease (CJD). However, studies on presymptomatic individuals remain limited. This study aimed to examine metabolic network topology reconfiguration in asymptomatic carriers of the PRNP G114V mutation.
View Article and Find Full Text PDFNatural products isolated from have attracted considerable attention from the chemical community due to their unique structures and promising anti-HIV activities. Recent progresses in the isolation and bioactivity studies for these natural molecules were summarized comprehensively. From the 23 previously uncharacterized compounds isolated from the plant , litseaverticillol B demonstrated the most potent anti-HIV activity , with IC ranging from 2 to 3 μg/mL.
View Article and Find Full Text PDFIntroduction: Fufang Shenqi Oral Liquid (FFSQOL) is an important Chinese medicine compound preparation with a wide range of clinical applications, which is mainly used to regulate immune function, improve cardiovascular function, and have anti-inflammatory and antibacterial effects. At present, it is of great importance to establish the quality evaluation method of FFSQOL and to investigate its quality markers (Q-markers).
Objectives: The aim of this study is to establish a quality evaluation method for FFSQOL and screen its Q-markers to provide a scientific basis for its quality control.
Article Synopsis
- Caffeic acid-3-O-methyltransferase (COMT) is essential for melatonin production in plants, with the study focusing on the GhCOMT33D gene in upland cotton.
- Silencing GhCOMT33D through virus-induced gene silencing (VIGS) resulted in reduced melatonin levels, leading to decreased resistance to cadmium (Cd) stress in cotton plants.
- The study observed that silenced plants exhibited poor physiological responses, including increased ROS and MDA levels, reduced stomatal openings, and visible damage to leaves, while non-silenced plants maintained higher melatonin levels and better health.
Article Synopsis
- - The study examines various fertilizer combinations (from no fertilizer to different mixes of chemical and organic fertilizers) and their effects on cotton yield and soil quality over a 10-year period.
- - Results indicated that the combination of 75% chemical and 25% organic fertilizer (M1) produced the highest cotton yield, while the 50% chemical and 50% organic fertilizer (M2) offered the best long-term sustainability in yield.
- - Key soil health indicators, like organic matter and nitrogen levels, improved significantly under the M1 treatment, suggesting effective fertilization strategies are crucial for maintaining soil quality and crop productivity.