Publications by authors named "H Nakadate"

In this paper the effectiveness of the support system which predicts the risk of the repetitive brain concussion is studied biomechanically. In the risk prediction system, the accident that caused the concussion is reconstructed by analyzing the game video via multibody dynamics and the resulting brain injury is calculated in detail by the finite element method. In order to calculate the aggravation of the brain injury by the repeated brain concussion, the following two methods are examined.

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Background: Pure red cell aplasia (PRCA) is a hematological disorder characterized by anemia with severe reticulocytopenia caused by a marked reduction in erythroid precursors in the bone marrow. PRCA is known to be associated with pregnancy, but thymoma-associated PRCA during pregnancy is very rare, and its successful management has not been reported.

Case Presentation: A 37-year-old primiparous woman with severe anemia was referred to our center at 27 weeks' gestation.

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Article Synopsis
  • Inhibitor-development is a major complication for patients with haemophilia, and this study aimed to explore the factors influencing this problem among Japanese patients.
  • The study involved 417 newly diagnosed patients, revealing that 31% of severe haemophilia A patients developed inhibitors, primarily detected within the first 25 treatment days.
  • Key findings indicated that genetic factors and treatment regimens, especially prophylaxis, significantly impacted inhibitor-development, with associations found between certain gene variants and the likelihood of developing inhibitors.
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A central venous access device (CVAD) was implanted in a child with hemophilia for long-term replacement therapy with factor VIII. Four years and eight months after its insertion, malfunction was observed. Further study revealed migration of the transected catheter to both the pulmonary arteries.

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