Publications by authors named "H Nagayoshi"
Background: The triglyceride-glucose index (TyG index), calculated as the logarithmic product of fasting triglyceride and glucose concentrations, is recognized as a simple marker of insulin resistance. However, the association between the TyG index and future decline of renal function remains unclear in the general population.
Objective: To investigate whether the TyG index was associated with future decline of renal function in the general population who had not progressed to chronic kidney disease stage G2.
Article Synopsis
- Quantum computers need to protect information from errors, which can be done by encoding it into a logical state suitable for quantum error correction.
- The Gottesman-Kitaev-Preskill (GKP) qubit is a strong candidate for this purpose due to its multiqubit operations that work well at optical frequencies.
- This research successfully demonstrated a GKP state using propagating light at telecommunication wavelengths, showing promising results in nonclassicality and non-Gaussianity, which are essential for future quantum computing developments.
Electrocardiographic left ventricular hypertrophy (LVH) could predict adverse renal outcomes in patients with hypertension. This study aimed to investigate the association between electrocardiographic LVH and future decline in renal function in the general population using a dataset of population-based health checkups from 2010 to 2019 including 19,825 participants. Electrocardiographic LVH was defined according to the Minnesota code.
View Article and Find Full Text PDFNaringenin, an initial synthesized flavanone in various plant species, is further utilized for production of many biologically active flavonoids, e.g., apigenin, eriodictyol, and genistein, by various plant enzymes including cytochrome P450s (P450s or CYPs).
View Article and Find Full Text PDFArticle Synopsis
- The study examines the oxidation of specific flavones (3'-methoxyflavone, 4'-methoxyflavone, and 3',4'-dimethoxyflavone) by human cytochrome P450 enzymes 1B1 and 2A13 using LC-MS/MS technology.
- 3'-Methoxyflavone and 4'-methoxyflavone underwent demethylation primarily with CYP1B1, resulting in 3'-hydroxyflavone and 4'-hydroxyflavone formation, while CYP2A13 was less effective.
- The introduction of 5,7-dihydroxyl groups in these compounds reduced their oxidation rates by