Publications by authors named "H Nagatsuka"
Article Synopsis
- Limited research exists on coronal cementum formation, particularly in impacted wisdom teeth.
- A histological and analytical examination of an impacted wisdom tooth from a 46-year-old female revealed widespread coronal cementum on the enamel with connections between them.
- Findings suggest that the presence of reduced enamel epithelium may be linked to coronal cementogenesis in impacted teeth, highlighting differences in the types of cementum formed.
Article Synopsis
- The study investigated how exercise in low oxygen (hypoxic) and normal oxygen (normoxic) conditions affects gastric emptying and intestinal cell damage in healthy males.
- Participants ran for 60 minutes at 70% of their maximum speed, with slower running and delayed gastric emptying observed in hypoxic conditions.
- Despite increased nausea and some indicators of intestinal damage being assessed, no significant differences in plasma levels of stress hormones were found between the two conditions, suggesting hypoxia can hinder digestive functions during endurance exercise.
Article Synopsis
- Some forms of Sjögren's syndrome (SS) cause systemic symptoms due to lymphocyte infiltration in various organs, which the study seeks to understand better using minor salivary gland tissues.
- The research involved a retrospective analysis of labial gland biopsies from female patients over 60 years old, combining clinical data with molecular techniques for gene expression and tissue imaging.
- Results revealed that secondary SS showed more severe epithelial damage and lymphocyte activity compared to primary SS, indicating that analyzing these FFPE samples can reveal significant histological differences between the two types of SS.
The polarization balance of M1/M2 macrophages with different functions is important in osteogenesis and bone repair processes. In a previous study, we succeeded in developing honeycomb tricalcium phosphate (TCP), which is a cylindrical scaffold with a honeycomb arrangement of straight pores, and we demonstrated that TCP with 300 and 500 μm pore diameters (300TCP and 500TCP) induced bone formation within the pores. However, the details of the influence of macrophage polarization on bone formation using engineered biomaterials, especially with respect to the geometric structure of the artificial biomaterials, are unknown.
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- The study addresses the challenge of inconsistent labeling in medical images, which affects diagnosis using deep learning models, particularly for oral exfoliative cytology.
- Researchers developed a convolutional neural network (CNN) by using annotations from multiple oral pathologists, processing six whole-slide images into 14,535 labeled tiles.
- The probabilistic model outperformed other approaches, achieving the highest classification performance and accuracy, suggesting that this method could enhance the reliability of AI in capturing diverse medical diagnoses.