Segregated neural explants exhibit co-oriented, asymmetric, neurite outgrowth.

Explants of embryonic chick sympathetic and sensory ganglia were found to exhibit asymmetric radial outgrowth of neurites under standard culture conditions with or without exogenous Nerve Growth Factor [NGF]. Opposing sides of an explant exhibited: a) differences in neurite length and, b) differences in neurite morphology. Strikingly, this asymmetry exhibited co-orientation among segregated, neighboring explants.

Development of a tool for the evaluation of obesity prevention partnerships.

Issue Addressed: Working in partnership is advocated as a necessary process to achieve shared goals in complex policy areas, yet little effort is dedicated to evaluating how well partnerships are functioning. This study describes the development and psychometric properties of a partnership assessment tool and illustrates its use in an obesity prevention partnership.

Methods: A literature scoping review was conducted on existing partnership assessment tools and used to develop a new tool, which was tested using the ACT whole-of-government Healthy Weight Initiative at two timepoints.

Full-length apolipoprotein E protects against the neurotoxicity of an apoE-related peptide.

Apolipoprotein E was found to protect against the neurotoxic effects of a dimeric peptide derived from the receptor-binding region of this protein (residues 141-149). Both apoE3 and apoE4 conferred protection but the major N-terminal fragment of each isoform did not. Nor was significant protection provided by bovine serum albumin or apoA-I.

Microtensile bond strengths of one-step and self-etching adhesive systems.

The microtensile bond strength of resin composite bonded to human enamel was evaluated utilizing four light-cure bonding agents. Human third molars were embedded in auto-cure acrylic and the buccal surfaces were sequentially abraded to 400 grit. Resin composite cylinders were then bonded using the four bonding systems according to the manufacturer's specifications.