Possible eucynodont (Synapsida: Cynodontia) tracks from a lacustrine facies in the Lower Jurassic Moenave Formation of southwestern Utah.

Eight fossil tetrapod footprints from lake-shore deposits in the Lower Jurassic Moenave Formation at the St. George Dinosaur Discovery Site (SGDS) in southwestern Utah cannot be assigned to the prevalent dinosaurian (, , , , ) or crocodyliform () ichnotaxa at the site. The tridactyl and tetradactyl footprints are incomplete, consisting of digit- and digit-tip-only imprints.

Polygenic risk for depression and anterior and posterior hippocampal volume in children and adolescents.

Background: Depression has frequently been associated with smaller hippocampal volume. The hippocampus varies in function along its anterior-posterior axis, with the anterior hippocampus more strongly associated with stress and emotion processing. The goals of this study were to examine the associations among parental history of anxiety/depression, polygenic risk scores for depression (PGS-DEP), and anterior and posterior hippocampal volumes in children and adolescents.

Acute and chronic effects of the organophosphate malathion on the pancreatic α and β cell viability, cell structure, and voltage-gated K currents.

Studies indicate that the pesticide malathion may have a role in diabetes. Herein, we determined the effects of different concentrations of malathion on survival, ultrastructure, and electrophysiologic islet cell parameters. Acutely, high concentrations of malathion (0.

Educational attainment polygenic scores, socioeconomic factors, and cortical structure in children and adolescents.

Genome-wide polygenic scores for educational attainment (PGS-EA) and socioeconomic factors, which are correlated with each other, have been consistently associated with academic achievement and general cognitive ability in children and adolescents. Yet, the independent associations of PGS-EA and socioeconomic factors with specific underlying factors at the neural and neurocognitive levels are not well understood. The main goals of this study were to examine the unique contributions of PGS-EA and parental education to cortical structure and neurocognitive skills in children and adolescents, and the associations among PGS-EA, cortical structure, and neurocognitive skills.

Selective Inhibition of -Methyl-d-aspartate Receptors with GluN2B Subunit Protects Cells against Stress-Induced Apoptotic Cell Death.

Participation of -methyl-d-aspartate (NMDA) receptors (NMDARs) in the failure of pancreatic cells during development of type 2 diabetes mellitus is discussed. Our study investigates whether cell mass and function can be preserved by selectively addressing the GluN2B subunit of the NMDAR. NMDAR activation by NMDA and its coagonist glycine moderately influenced electrical activity and Ca handling in islet cells at a threshold glucose concentration (4-5 mM) without affecting glucose-mediated insulin secretion.