Paget's disease of the vulva and urogenital malignancies: a case report and review of the literature.

The vulva is one of the extramammary sites which has a potential for developing Paget's Disease with which an underlying sweat gland carcinoma or breast carcinoma is frequently associated. Urogenital malignancy may be a third contender. Such a case managed by the authors herein reported and a review of the literature about such lesions support this assumption.

Granular cell tumor of the clitoris in pregnancy.

Granular cell tumors of the female genital organs represent 7-15% of all granular cell tumors reported in the literature. The majority of these genital lesions are located on the vulva. Granular cell tumor involving the clitoris is extremely rare and should be considered in the differential diagnosis of clitoral masses.

Basaloid carcinoma of uterine cervix.

Basaloid carcinoma is an uncommon tumor of the uterine cervix which has received little recognition in the medical literature. It is characterized by: 1) an ulcerated infiltrating growth pattern, 2) nests or cords of small basaloid cells, 3) prominent peripheral palisading of cells in the tumor nests, and 4) no significant stromal reaction. This cervical neoplasm is an entity distinguishable from adenoid cystic carcinoma, undifferentiated small-cell carcinoma, carcinoid tumor, and regional basaloid patterns in otherwise typical squamous cell carcinoma.

Pulmonary structural changes following microembolism and blood transfusion. A light and electron microscopic study.

Blood stored under standard blood band conditions develops microaggregates of platelets and leukocytes. Dog lungs were studied by light and electron microscopy at intervals from 48 hours to six days following exchange transfusions of sublethal volumes of such microaggregate-rich blood through either standard or Dacron wool (Swank) transfusion filters. After transfusion through standard filters, the pulmonary microvasculature was extensively occluded by microemboli.

Functional ovarian tumors of stromal and sex cord origin.

Most functional ovarian tumors are of specific stromal or sex cord origin, capable of differentiating in either a female direction or, less commonly, a male direction. Tumors of stromal origin such as thecoma, stromal luteoma, and Leydig cell tumors are for all practical purposes benign, and evolve from mature ovarian stroma, recapitulating common non-neoplastic transformations such as stromal changes associated with follicle development and nodular stromal hyperplasia. Sex cord tumors of granulosa or Sertoli cell types are generally of a low order of malignancy, tending to late recurrence, occasional peritoneal seeding, and only rarely to distant metastasis.