Early detection of cancer biomarkers is crucial for effective diagnosis and treatment, prompting the development of an ultrasensitive label-free electrochemical immunosensor. In this study, we fabricated an ultrasensitive label-free electrochemical immunosensor using a glassy carbon electrode/gold nanoparticles (GCE/AuNPs) modification for quantification of osteopontin (OPN), an oncomarker. The surface features of the modified electrodes were confirmed using scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS) methods.
View Article and Find Full Text PDFAcne is a persistent infectious skin condition primarily caused by Propionibacterium acne that affects 80 % of teenagers. The rise of antibiotic resistance in P. acnes has led to an increasing interest in exploring alternative antimicrobial agents.
View Article and Find Full Text PDFIn recent decades, there has been a concerning and consistent rise in the incidence of cancer, posing a significant threat to human health and overall quality of life. The transferrin receptor (TfR) is one of the most crucial protein biomarkers observed to be overexpressed in various cancers. This study reports on the development of a novel voltammetric immunosensor for TfR detection.
View Article and Find Full Text PDFAn assortment of environmental matrices includes arsenic (As) in its different oxidation states, which is often linked to concerns that pose a threat to public health worldwide. The current difficulty lies in addressing toxicological concerns and achieving sustained detoxification of As. Multiple conventional degradation methods are accessible; however, they are indeed labor-intensive, expensive, and reliant on prolonged laboratory evaluations.
View Article and Find Full Text PDFHerein, we fabricated an ultrasensitive electrochemical immunosensor for the quantitative detection of corticosteroid-binding globulin (CBG). CBG is a protein that regulates glucocorticoid levels and is an important biomarker for inflammation. A decrease in CBG levels is a key biomarker for inflammatory diseases, such as septic shock.
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