Publications by authors named "H Mortensen"
Background: In Malawi, approximately 25% of adolescents living with HIV (ALWH) also suffer from depression. Not only is HIV stigma a major contributor to depression but it also adversely impacts HIV care engagement. ALWH can experience HIV stigma as stereotyping, social exclusion, low social support, and abuse, and these experiences are associated with poor mental health.
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- - Concerns over the safety of engineered nanomaterials (ENMs) are rising as their use expands, prompting the need for research into their potentially harmful effects.
- - The US EPA's Office of Research and Development created NaKnowBase (NKB), a database that compiles data from various studies on the environmental health and safety impacts of ENMs.
- - The article details a study that uses quantitative structure-activity relationship (QSAR) analysis and a decision tree method to predict the effects of ENMs on cell viability, with validation through the Jaqpot cloud platform for global collaboration.
Article Synopsis
- The National Nanotechnology Initiative held a Nanoinformatics Conference in 2023, discussing collaborations between the U.S. and EU on handling nanotechnology data.
- They talked about creating databases, their pros and cons, and how to improve standards for sharing and storing information about nano Environmental Health and Safety (nanoEHS).
- Important topics that were missed include evaluating data usage, including community input, and integrating new data types like micro and nano plastics for better future progress.
The massive production and application of nanomaterials (NMs) have raised concerns about the potential adverse effects of NMs on human health and the environment. Evaluating the adverse effects of NMs by laboratory methods is expensive, time-consuming, and often fails to keep pace with the invention of new materials. Therefore, methods that utilize machine learning techniques to predict the toxicity potentials of NMs are a promising alternative approach if regulatory confidence in them can be enhanced.
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- A systematic review and meta-analysis was conducted to evaluate the effectiveness of proton beam therapy (PBT) for treating hepatocellular carcinoma (HCC), focusing on recent data from various medical databases.
- The analysis included 1,858 HCC patients from 22 studies between 2004 and 2023, revealing a high local progression-free survival rate of 88% at 3 years and 86% at 5 years, with low rates of severe hepatic toxicity.
- The findings suggest that PBT offers favorable long-term outcomes for HCC patients with minimal side effects, but further research is needed to determine which specific patient groups benefit the most from this treatment.