Publications by authors named "H Moriwaki"
Article Synopsis
- The fragment molecular orbital (FMO) method efficiently analyzes large biomolecules by breaking them into smaller fragments and calculating their interaction energies, which helps understand molecular recognition.
- A graphical user interface was developed to facilitate manual fragmentation of small molecules and enhance the workflow for FMO calculations in the Molecular Operating Environment (MOE).
- The study demonstrated effective fragmentation and interaction analyses for complex cases like cysteine-ligand bonding in SARS-CoV-2 and metal coordination in peptides, indicating potential for advancements in drug discovery.
A simple method for purifying water using household items has been developed. The solution containing an environmental pollutant was added to the PET bottle. The lid of the PET bottle was closed, and the bottle was then placed with the lid down in a freezer for 9 h.
View Article and Find Full Text PDFMuscle-Protective Effect of Carnosine against Dexamethasone-Induced Muscle Atrophy in C2C12 Myotube.
J Nutr Sci Vitaminol (Tokyo)
June 2024
Article Synopsis
- * Treatment with carnosine reduced the expression of proteins associated with muscle atrophy and oxidative stress, while the components L-histidine and β-alanine did not show similar benefits.
- * The study suggests that carnosine could be a promising therapeutic option for preventing Dex-induced muscle loss, unlike its individual components L-histidine and β-alanine.