Publications by authors named "H Mone"
We report a patient with urogenital schistosomiasis and three cases of subclinical infection within one family acquired from Solenzara River, Corsica, in 2019. Our cases confirm that transmission of schistosomiasis in Corsica is ongoing and has been extended from the Cavu River to the Solenzara River. Solenzara River is clearly a transmission site for schistosomiasis in Corsica.
View Article and Find Full Text PDFObjective: This study aims to (i) analyse whether speleothems may contain fossil parasitic worm eggs and, if so, (ii) identify the pathogens involved, and (iii) place them in geological, palaeontological, and chronological contexts to know the zoonoses that could affect human and animal populations during the Middle Pleistocene.
Materials: A sample of calcite dated to the beginning of MIS 9 and MIS 8 from the Bàsura cave (Liguria, Italy) was analysed.
Methods: The chemical protocol applied is characterised using hydrochloric acid, the reduction of hydrofluoric acid application time, and by the absence of the use of base, dense liquor or acetolysis.
In living cells, the genetic information stored in the DNA sequence is always associated with chromosomal and extra-chromosomal epigenetic information. Chromatin is formed by the DNA and associated proteins, in particular histones. Covalent histone modifications are important bearers of epigenetic information and as such have been increasingly studied since about the year 2000.
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- - Mass drug administration with praziquantel (PZQ) is the primary method used to control schistosomiasis, but many parasites show reduced sensitivity to the drug, leading researchers to study the genetic factors behind this resistance in a specific PZQ-selected population.
- - The study identified a gene related to a transient receptor potential (TRPM) channel that influences how schistosomiasis parasites respond to PZQ, revealing a significant difference in PZQ resistance levels between resistant and sensitive parasite populations.
- - By analyzing genetic variations in the TRPM channel across different global parasite samples, researchers discovered a mutation that prevents PZQ from binding, highlighting the need for monitoring these resistant strains in efforts to eliminate schistos
Cercarial emission of schistosomes is a determinant in the transmission to the definitive host and constitutes a good marker to identify which definitive host is responsible for transmission, mainly in introgressive hybridization situations. Our goal was to test the hypothesis that micro-mammals play a role in Schistosoma haematobium, S. bovis, and/or S.
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