Illuminating the impact of CD38-induced adenosine formation in B-cell lymphoma.

The expression of CD38 by cancer cells may mediate an immune-suppressive effect by producing Extracellular Adenosine (ADO) acting through G-protein-coupled cell surface receptors on cellular components and tumor cells. This can increase PD-1 expression and interaction with PD-L1, suppressing CD8 + cytotoxic T cells. This study examines the impact of heightened CD38 expression and extracellular ADO on various hematological and clinical parameters in patients with mature B-cell lymphoma, alongside their correlation with the soluble counterparts of the PD-1/PD-L1 axis.

Incidental detection of pulmonary lymphangitis carcinomatosis in an old adult: An exceedingly rare case report.

Introduction And Importance: Pulmonary lymphangitis carcinomatosis (PLC) is a rare and aggressive condition that silently spreads cancer cells through the lungs' lymphatic system. Often linked to advanced malignancies, PLC often mimics other pulmonary diseases, making diagnosis challenging. This report shares the unique case of an asymptomatic patient whose routine follow-up imaging led to the early discovery of PLC, highlighting the life-saving potential of attentive medical care.

Coexistence of adenomyomatosis in a left-sided gallbladder: a case report.

Introduction: The coexistence of gallbladder (LSG) and adenomyomatosis (ADM) is extremely uncommon presenting a novel clinical dilemma that has not been previously documented. LSG refers to a anomaly where the gallbladder is situated to the left of the round ligament deviating from its usual position. This anomaly is rare, with reported occurrences ranging between 0.

From asthma exacerbation to pulmonary mucoepidermoid carcinoma: A rare case report.

Introduction And Importance: Pulmonary mucoepidermoid carcinoma (PMEC) is a rare lung tumor, accounting 0.1-0.2 % of lung malignancies, commonly affecting adults under 50.

An unusual presentation of primary synovial sarcoma of the ethmoid sinus in a 54-year-old woman: A case report and literature review.

Introduction And Importance: Synovial sarcoma is a malignant soft tissue tumor primarily affects the extremities. Its presence in the paranasal sinuses, especially within the ethmoid sinus, is exceedingly rare.

Case Presentation: We report a case of monophasic synovial sarcoma of the ethmoid sinus in a 54-year-old woman, who presented with 3 months history of left eye pain and bulging.