Publications by authors named "H Miyako"
Article Synopsis
- The study challenges the traditional view that humoral immunity is not important in fighting tumors, revealing that B cells are actively involved in breast cancer through both antibody production and immunosuppressive roles.
- Researchers examined blood samples from 27 breast cancer patients and 12 healthy donors to explore B-cell differentiation using specific cell surface markers.
- Results showed that breast cancer patients had a significantly higher level of total B cells, especially memory B cells, indicating a notable difference in B-cell profiles between cancer patients and healthy individuals.
Metastatic tumors of the small intestinal tract from extra-abdominal sites are rare. We report herein a rare case of small intestinal metastasis from esophageal carcinoma that presented with perforated peritonitis. A 71-year-old man with dysphagia was referred to our hospital for further examination and treatment, and was diagnosed with type 3 advanced esophageal squamous cell carcinoma of the lower thoracic esophagus.
View Article and Find Full Text PDFAconite tuber is a representative crude drug for warming the body internally in Japanese Kampo medicine and Chinese traditional medicine. The crude drug is used in major prescriptions for the aged. Varieties of Aconitum plants are distributed throughout the Japanese Islands, especially Hokkaido.
View Article and Find Full Text PDFThe glycoprotein laminin 5γ2 chain (LN-5γ2) has recently become a focus of increased interest and investigation as a marker of invasion in gastrointestinal malignancies. We investigated the significance of LN-5γ2 expression as a prognostic factor in superficial esophageal cancer. The study population consisted of 87 patients who had undergone a transthoracic esophagectomy and three-field lymphadenectomy for the treatment of superficial esophageal cancer at Tokai University Hospital.
View Article and Find Full Text PDFBackground: While the benefit of passive immunotherapy is commonly accepted, active immunization may have advantages for the patient's quality of life. We identified a new epitope of Mab CH401 against Her-2/neu extracellular domain (N: 167-175), and evaluated the effect of active immunization of the 20mer peptide containing the epitope (CH401 peptide).
Materials And Methods: Epitope-mapping was performed using ELISA with Her-2/neu-related multiple antigen peptides (MAP).