Synthesis and Characterization of Mesoporous Materials Functionalized with Phosphinic Acid Ligand and Their Capability to Remove Cd(II).

This article presents a study of cadmium removal from nitrate medium using adsorption in calcined mesoporous silica (MCM-C), mesoporous silica doped (MCM_DIOPA), and calcined and impregnated mesoporous silica (MCM@DIOPA), with diisooctylphosphinic acid (DIOPA). The sorbents were synthesized via a sol-gel method. Several characterization techniques, such as XRD, FTIR spectroscopy, N sorption and elemental analysis, have been used to determine the main structural, textural, and chemical properties of prepared sorbents.

Exportin 1-mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's lymphoma.

Exportin 1 (XPO1) is the main nuclear export receptor that controls the subcellular trafficking and the functions of major regulatory proteins. XPO1 is overexpressed in various cancers and small inhibitors of nuclear export (SINEs) have been developed to inhibit XPO1. In primary mediastinal B-cell lymphoma (PMBL) and classical Hodgkin's lymphoma (cHL), the XPO1 gene may be mutated on one nucleotide and encodes the mutant XPO1 .

Mutation Modifies Exportin 1 Localisation and Interactome in B-cell Lymphoma.

The gene encodes exportin 1 (XPO1) that controls the nuclear export of cargo proteins and RNAs. Almost 25% of primary mediastinal B-cell lymphoma (PMBL) and classical Hodgkin lymphoma (cHL) cases harboured a recurrent point mutation (NM_003400, chr2:g61718472C>T) resulting in the E571K substitution within the hydrophobic groove of the protein, the site of cargo binding. We investigated the impact of the mutation using PMBL/cHL cells having various statuses and CRISPR-Cas9-edited cells in which the E571K mutation was either introduced or knocked-out.

Lanthanide recovery by silica-Cyanex 272 material immobilized in alginate matrix.

Mesoporous silica impregnate with Cyanex 272 (bis/2,4,4-trimethylpentyl/phosphinic acid) extractant was immobilized into an alginate matrix to obtain a composite sorbent easy to use and applicable in fixed-bed column continuous systems. The sorption efficiency of this material was tested for the recovery of Eu(III) ions from aqueous solutions in batch and continuous mode. The competition among rare earths ions (europium, lanthanum, and lutetium) and among rare earths and calcium or sodium ions was investigated.

Removal of Zinc from Aqueous Solutions Using Lamellar Double Hydroxide Materials Impregnated with Cyanex 272: Characterization and Sorption Studies.

Removal of heavy metals from wastewater is mandatory in order to avoid water pollution of natural reservoirs. In the present study, layered double hydroxide (LDH) materials were evaluated for removal of zinc from aqueous solutions. Materials thus prepared were impregnated with cyanex 272 using the dry method.