[Tumor markers for bladder cancer: up-to-date study by the Kiel Tumor Bank].

Introduction: The number of noninvasive diagnostic tests for bladder cancer has increased tremendously over the last years with a large number of experimental and commercial tests. Comparative analyses of tests for diagnosis, follow-up, and recurrence detection of bladder cancer were performed retrospectively as well as prospectively, unicentrically, and multicentrically.

Methods: An analysis of multicentric studies with large patient numbers compared with our own Kiel Tumor Bank data is presented.

[Acute idiopathic scrotal edema: a rare or underdiagnosed disease?].

We present a case of acute idiopathic scrotal oedema diagnosed after surgical scrotal exploration and we discuss its incidence, differential diagnoses and indication of surgery for acute scrotum with boys.

Neoadjuvant chemotherapy with cisplatin and methotrexate in patients with muscle-invasive bladder tumours.

This prospective, randomized study based on two associated trials was designed to evaluate the effect of neoadjuvant chemotherapy with cisplatin and methotrexate with folinic acid rescue or no chemotherapy prior to local treatment in patients with T2-T4b, NX-3, MO transitional cell carcinoma of the bladder. In the first trial, local treatment consisted of cystectomy (DAVECA 8901) and in the other trial the treatment was radiotherapy (DAVECA 8902); 153 eligible patients were randomized. The majority of the patients (89%) completed the protocol.

[Urogenital tuberculosis in Danes].

Extrapulmonary tuberculosis is rare in natives of Denmark, who are not exposed to risk factors, such as homelessness and drug or alcohol abuse. Two patients diagnosed with advanced urogenital tuberculosis are reported.