Publications by authors named "H Mehtap Kutlu"
Investigation of ADAMTS-13 levels in patients with COVID-19 infection.
J Infect Dev Ctries
September 2024
Article Synopsis
- COVID-19 patients have a higher risk of blood clotting issues, possibly linked to ADAMTS-13 levels, a protein that helps regulate blood clotting.
- A study on 180 patients categorized them into mild and severe COVID-19 groups, comparing their ADAMTS-13 levels with a control group, using various clinical tests.
- Results showed no significant differences in ADAMTS-13 levels between the groups, suggesting that it may not be a reliable biomarker for assessing patient risk upon admission.
Introduction: Metabolic syndrome (MetS) manifests resembling pathophysiological mechanisms with Parkinson's disease (PD). Current research on the overall population has emphasized MetS as a freestanding risk factor for cognition. This research aims to explore the impact of MetS on cognition in Parkinson's patients.
View Article and Find Full Text PDFBackground: Ceranib-2, an acid ceramidase (AC) inhibitor, can inhibit cancer cell proliferation and tumor development. However, poor water solubility and low cellular bioavailability limit its efficacy in cancer treatment.
Methods And Results: This study aimed to investigate the cell death induced by ceranib-2 and its solid lipid nanoformulation (ceranib-2-SLN) produced by the hot homogenization technique and the synergistic relationship between ceramide and telomerase in vitro and in silico.
Aim: To evaluate the cytotoxic and proapoptotic effects of C6 ceramide on the C6 rat glioma cell line.
Material And Methods: The C6 rat glioma cell line was evaluated. Using a confocal microscope and the appropriate software, the cytotoxic effects of C6 ceramide were identified using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H tetrazolium bromide (MTT) colorimetric experiments.
Purpose: The aim of this study is to evaluate the presence of candida, which is one of the etiological factors contributing to early childhood caries (ECC) and severe early childhood caries (S-ECC), in the dental plaque and saliva of children aged 6 years and younger.
Materials And Methods: Our study involved 60 participants who met the inclusion criteria. Based on clinical examinations, we divided them into three groups, each consisting of 20 children: S-ECC, ECC, and caries-free groups.