Publications by authors named "H Mecke"

Article Synopsis
  • A study evaluated the effectiveness of human epididymis protein 4 (HE4), cancer antigen 125 (CA125), and the risk of malignancy algorithm (ROMA) in detecting ovarian cancer in patients with a pelvic mass, alongside traditional ultrasound methods.
  • Among 965 patients, those with advanced-stage ovarian cancer showed excellent biomarker performance (AUC > 0.92), but the diagnostic accuracy was lower for early-stage cancers (AUC < 0.77).
  • ROMA and HE4 were especially useful in distinguishing ovarian cancer from endometriosis in premenopausal women, while CA125 was found to be more reliable for postmenopausal patients.
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Objective: The prognosis for ovarian cancer patients remains poor. A key to maximizing survival rates is early detection and treatment. This requires an accurate prediction of malignancy.

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Objective: To assess the risks of complications including intraoperative spillage following laparoscopic dermoid cyst enucleation.

Study Design: A retrospective case series comparison of 390 patients who had surgery at our hospital from 1992 to 1998 for teratomas of the ovary.

Results: 43 patients were treated with laparotomy.

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Even today, the situation is still unclear with regard to the radicality of the operation and any adjuvant therapy required in treatment of borderline tumors of the ovary. In the last two decades, treatment of these tumors in the Department of Gynecology and Obstetrics at our hospital has depended on the stage of the disease and the age of the patient. It ranged from laparoscopic cyst extirpation to hysterectomy with bilateral adnectomy and omental resection and regional lymphnodectomy.

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From 1987 to 1991 a total of 5035 pelviscopies were done at the Kiel University Hospital of Gynaecology. More than 90% of these were surgical pelviscopies, whereas less than 10% were diagnostic procedures only. Serious complications requiring laparotomy or repeat pelviscopy or laparotomy within 4 weeks after the original procedure, occurred in 2.

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