Publications by authors named "H McBride"

Article Synopsis
  • Lewy bodies (LBs), which are linked to Parkinson's disease (PD), can be formed in human dopaminergic neurons derived from induced pluripotent stem cells (iPSCs) when exposed to α-synuclein fibrils and immune challenges.
  • Immune response factors like interferon-γ and interleukin-1β, along with activated microglia, play a critical role in promoting this inclusion formation and impair lysosomal function.
  • The study suggests that LB-like inclusions may arise from disruptions in autophagy, highlighting a possible connection between immune dysfunction and PD development.
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Objective: The purpose of the study was to determine average tensile forces resulting in suture failure while tying a knot during repair of complete radial meniscus tears and to compare the failure tensile force based on meniscus tissue location: the peripheral (red-red) versus inner (white-white).

Design: This study was designed as a cadaveric biomechanical study using 24 menisci harvested from fresh frozen cadaveric knees with midbody radial tears. Tears were repaired using 2-0 nonabsorbable suture in both the inner meniscus and the peripheral meniscus.

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Background: In phenylketonuria (PKU), attending multidisciplinary clinic reviews is an important aspect of life-long care. Since the COVID-19 pandemic, video and telephone clinics are used as alternative methods for people with PKU to have contact with their care team. There is limited research concerning patient preference, experience and perceptions of alternative types of clinic review.

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A commercial triple-strain -based probiotic was tested to determine its effect on the colonization of the ceca by Enteritidis (SE) in commercial layer pullets. Two treatments were tested, each with containing 128 day-of-hatch LSL layer chicks. On top of a standard diet: 1) no supplement (Control, CON), and 2) Probiotic (GalliPro® Fit, 500 g/MT, 1.

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Compared to the large body of maternal mental health research for other pediatric disorders, we know far less about the experience of mothers of children with 22q11DS. This study investigates the coping methods, protective factors, and mental health of this population. These findings might lead to better support for 22q11DS maternal mental health.

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