[Changes in the cell cycle in breast cancer].

Recent advances in the mechanisms of oncogenesis have revealed a close relationship between the cell cycle and apoptosis. The cell cycle goes through a series of kinases and fosfatases activities that enhance the cyclins. In the mammalian cells, the kinases CDK4/6, CDK2, CDK2 and p34 are linked to the cyclins D, E, A, and B When the cell goes from the phase G1 toward mitosis.