Frequency of Cryptosporidium spp. as cause of human gastrointestinal disease in Switzerland and possible sources of infection.

Detection of Cryptosporidium parvum is not routinely done in laboratories of clinical microbiology and there is no obligation to communicate isolations of this pathogen to health authorities. For these reasons, frequency of cryptosporidiosis and sources of infection are only poorly known in Switzerland. To obtain more concise information in this field, feces from 5179 hospitalized and 1256 ambulatory patients with suspected gastrointestinal infections were screened for Cryptosporidium spp.

Role of adenoids in the pathogenesis of otitis media: a bacteriologic and immunohistochemical analysis.

Adenoidectomy is frequently performed in children suffering from recurrent or chronic otitis media with effusion and is thought to produce a long-term effect in preventing further episodes of otitis media. Bacteriologic analysis of adenoids from 60 patients revealed a significantly elevated colonization rate of middle ear pathogens in children with a present or previous history of ear disease compared to children with adenoidal hypertrophy only. The predominant pathogen was nontypeable Haemophilus influenzae, followed by Streptococcus pneumoniae and Moraxella catarrhalis.

Prolonged hemodynamic benefits from a high-dose bolus injection of human atrial natriuretic factor in congestive heart failure.

The physiologic and potential pharmacologic roles of atrial natriuretic factor in congestive heart failure have remained confusing. We have evaluated the hemodynamic responses to human atrial natriuretic factor [ANF (102-126)] given as bolus intravenous doses of 2.0 or 4.

Bolus injections of synthetic atrial natriuretic peptide in patients with chronic renal failure or nephrotic syndrome.

The diuretic and natriuretic responses to exogenous synthetic atrial natriuretic peptide (ANP) were evaluated in patients with chronic renal failure (CRF) or nephrotic syndrome (NS). Patients were studied after an oral water load (8 ml/kg in CRF and 20 ml/kg in NS patients). A short intravenous bolus of either a placebo or ANP was administered when urine output was stable.