Publications by authors named "H Marchel"
Biofilms are microbial communities of surface-attached cells embedded in a self-produced extracellular matrix. They have been found to play a role in a wide variety of infections, including catheter-related urinary tract and bloodstream infections, and, therefore remain a significant source of morbidity and mortality among the world's population. Recently, much attention has been devoted to the prevention of biofilm formation on implant surfaces.
View Article and Find Full Text PDFGut colonization by antibiotic-resistant bacteria may underlie hard-to-treat systemic infections. There is also accumulating evidence on the immunomodulatory function of gut microbiota after allogeneic stem cell transplantation (alloSCT) and its impact on graft-versus-host disease (GVHD). We investigated the epidemiology and clinical impact of gut colonization after alloSCT and retrospectively analyzed data on 107 alloSCTs performed at a single transplant center.
View Article and Find Full Text PDF[Usefulness of wide-range microbiological diagnostics proceedings in case of simultaneous infection with four herpesviruses after allogeneic haematopoietic stem cell transplantation--a case report].
Med Dosw Mikrobiol
August 2014
Article Synopsis
- Immunocompromised individuals face significant health risks from various infections, as highlighted by a fatal case involving four herpesviruses in a 49-year-old male post-transplant patient.
- Microbiological examinations and real-time PCR assays were utilized to test clinical samples for viral DNA, revealing the presence of HSV-1, VZV, HHV-6, and EBV.
- Despite treatment with oral acyclovir, the viral loads of HSV-1 and VZV continued to rise, demonstrating the importance of real-time PCR for monitoring herpesviral infections in clinical settings.
Biodegradation of the outer silicone insulation of endocardial leads.
Circ Arrhythm Electrophysiol
April 2013
Background: Silicone catheter insulation, larynx prostheses undergo biodegradation. The aims of the study were to verify the conviction that outer silicone lead insulation is biostable and inert in addition to determining the role of macrophages (M) and Staphylococcus aureus (S aureus) strains in the silicone lead insulation degradation.
Methods And Results: Leads removed from 8 patients because of infective and noninfective indications were analyzed with stereomicroscope and classified according to Banacha abrasion classification, and additional analysis using scanning electron microscope was performed.
Microbial biofilms are considered as virulence factors. During the present study, 34 clinical strains of Acinetobacter baumannii, isolated from patients hospitalized in two tertiary care hospitals, were examined for biofilm formation. These strains showed high variability in biofilm formation.
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