Synthesis and crystal structure of (2)-1-[3,5-bis-(benz-yloxy)phen-yl]-3-(4-eth-oxy-phen-yl)prop-2-en-1-one.

In the title compound, CHO, the phenyl rings of the chalcone unit subtend a dihedral angle of 26.43 (10)°. The phenyl rings of the pendant benz-yloxy groups are orientated at 75.

Benzylidene-isophorone hybrids with strong anticancer activity.

Isophorone is a cyclic ketone that has gained significant attention in the field of organic chemistry due to its versatile reactivity and structural attributes. Derivatives of isophorone offer a broad spectrum of applications ranging from pharmaceuticals to polymer chemistry. With the aim of developing novel hybrid structures based on benzylidene by combining with isophorone scaffold, we report 3 derivatives of the benzylidene-isophorone hybrids and its potent anticancer activity.

Ethyl 2-cyano-2-{()-2-[2,2-di-cyano-1-(4-methyl-phen-yl)eth-yl]cyclo-hexyl-idene}acetate.

In the title compound, CHNO, the cyclo-hexane ring adopts a chair conformation. The methyl-phenyl ring is oriented at an angle of 36.2 (1)° with respect to the best plane of cyclo-hexane moiety.

One-pot Synthesis of 2-Hydroxy-1,4-Naphthoquinone (Lawsone).

Unlabelled: Aims and Scope: The 2-hydroxy-1,4-naphthoquinone (lawsone) and 2,5-dihydroxy-1, 4-naphthoquninone (5-hydroxylawsone) are synthesized by one step process. The process involves an inexpensive catalyst urea hydrogen peroxide and a base (t-BuOK) in alcohol for the transformation of 1-naphthol or 2,5-dihydroxynaphthalene to lawsone or its derivatives in the presences of oxygen. The process is further directed to produce lawsone or its derivatives, with no extraneous heating to make it energetically efficient.

Crystal structure of 2'-[(2',4'-di-fluoro-biphenyl-4-yl)carbon-yl]-1'-phenyl-1',2',5',6',7',7a'-hexa-hydro-spiro-[indole-3,3'-pyrrolizin]-2(1H)-one.

In the title pyrrolizidine derivative, C33H26F2N2O2, both pyrrolidine rings of the pyrrolizidine moiety adopt an envelope conformation. The di-fluoro-phenyl group is oriented at an angle of 54.3 (1)° with respect to the oxindole moiety.