Publications by authors named "H Mahdy-Abdallah"

Noise exposure is a health hazard in the textile industry. In cochlear hair cells, DNA damage caused by 8-oxoguanine (8-oxo G) can result in noise-induced hearing loss. Human 8-hydroxyguanine glycosylase (hOGG1) is a DNA repair enzyme that excises (8-oxo G) in the DNA and repairs DNA damage.

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  • * The study evaluated biomarkers like serum cystatin-c and urinary hemeoxygenase (HO-1) to predict kidney disease in T2DM patients, analyzing genetic factors such as ACE I/D polymorphism and ACE G2350A genotypes.
  • * Results showed elevated levels of cystatin-c and HO-1 in T2DM patients compared to controls, with specific genotypes (GG for ACE G2350A and DD for ACE I/D) linked to increased biomarkers, indicating potential early predictors of kidney injury.
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Objective: Workers in secondary aluminum production plants are occupationally exposed to polycyclic aromatic hydrocarbons (PAHs). We aimed to monitor the concentrations of PAHs in air and in serum of workers at two secondary aluminum production plants. We also investigated the potential risk of lung cancer development among PAHs exposed workers with emphasis on the role of A1AT mutation and APEX1 gene polymorphisms.

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In this study, the risk of Aspergillus (Asp.) positivity and its respiratory health impacts on wastewater treatment plant (WWTP) workers were studied. In addition, it identified the geno-susceptibility role of mannose-binding lectin 2 (MBL2) gene polymorphisms and the mannose-binding lectin (MBL) serum levels on the pulmonary functions of the Asp.

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  • * The research measured various biomarkers (like liver enzymes and oxidative stress indicators) in 100 pesticide-exposed workers and 100 matched controls, finding significant changes in enzyme levels and oxidative stress markers depending on exposure and location.
  • * The study concluded that specific gene polymorphisms (especially GSTT1) may increase susceptibility to liver toxicity from pesticides, highlighting the important role of genetic factors in occupational health risks.
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