Pifithrin-µ Induces Stress Granule Formation, Regulates Cell Survival, and Rewires Cellular Signaling.

(1) Background: Stress granules (SGs) are cytoplasmic protein-RNA condensates that assemble in response to various insults. SG production is driven by signaling pathways that are relevant to human disease. Compounds that modulate SG characteristics are therefore of clinical interest.

Comparison of Surgeons' Assessment of the Extent of Vestibular Schwannoma Resection with Immediate Post Operative and Follow-Up Volumetric MRI Analysis.

(1) Background: Incomplete excision of vestibular schwannomas (VSs) is sometimes preferable for facial nerve preservation. On the other hand, subtotal resection may be associated with higher tumor recurrence. We evaluated the correlation between intra-operative assessment of residual tumor and early and follow-up imaging.

Content Validity of a High-Fidelity Surgical Middle Ear Simulator: A Randomized Prospective International Multicenter Trial.

Objective: After demonstration of face validity of a surgical middle ear simulator (SMS) previously, we assessed the content validity of the simulator with otolaryngology residents.

Study Design: Multicenter randomized prospective international study.

Setting: Four academic institutions.

Facile synthesis of spongy NiCoO powders for lithium-ion storage.

Spongy NiCoO powders were prepared by solution combustion synthesis (SCS) method for lithium ions storage. The effects of combustion parameters including fuel type (L-lysine, glycine, and urea) and fuel amount on the lithium storage performance of NiCoO powders were analyzed by various characterization techniques. Single-phase NiCoO powders with extremely porous microstructure showed a strong drop of initial specific capacity up to 350 mAhg which was recovered up to 666 mAhg following 100 charge/discharge cycles.

Hypercoagulability in Vestibular Schwannoma Surgery.

Objective: Patients with vestibular schwannoma who harbor a genetic predisposition for venous thromboembolism require special consideration when determining optimal therapeutic management. The primary objective of the current study was to provide recommendations on treatment of hypercoagulable patients with vestibular schwannoma through a case series and review of the literature.

Patients: Two patients who underwent resection of vestibular schwannomas.