Publications by authors named "H Machida"
We herein describe a patient with non-small-cell lung cancer who achieved pCR with a single dose of pembrolizumab-based chemoimmunotherapy followed by surgery. A 61-year-old man was referred to our hospital with wheezing and an abnormal chest shadow. Squamous cell carcinoma of the left lower lobe, cT2aN1M0 stage IIB, was diagnosed and pembrolizumab-based chemoimmunotherapy was initiated at the patient's request.
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- - Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and early detection is difficult, prompting the development of a novel detection method called Comprehensive Serum Glycopeptide Spectral Analysis (CSGSA).
- - CSGSA identifies early-stage EOC by examining changes in glycan structures in serum glycoproteins alongside traditional tumor markers, achieving high accuracy (AUC of 0.924) in distinguishing early-stage EOC from controls.
- - This method significantly outperforms existing tumor markers, like CA125 and HE4, especially in differentiating early-stage ovarian clear cell carcinoma from endometrioma, showcasing strong potential for enhanced early detection of EOC.
Objective: To examine the efficacy and safety of minimally invasive surgery (MIS) and conventional abdominal surgery for epithelial ovarian cancer (EOC), stratified by treatment type.
Methods: A systematic review and meta-analysis were conducted by an Expert Panel of the Japan Society of Gynecologic Oncology Ovarian Cancer Committee. Several academic databases, including PubMed/MEDLINE, Cochrane Database, and Ichushi were searched by the Japan Medical Library Association on November 11, 2023, using the keywords "epithelial ovarian cancer", "minimally invasive surgery", "laparoscopic", and "robot-assisted".
Article Synopsis
- The study aimed to evaluate the oncologic outcomes of patients with early-stage, intermediate-risk cervical cancer after surgical treatment, focusing on various postoperative therapy types.
- Researchers analyzed data from 1,084 patients in a retrospective cohort study, categorizing them based on histology and recurrence risk after undergoing radical hysterectomy and lymphadenectomy.
- Results indicated that patients with no lympho-vascular space invasion had better 5-year disease-free survival rates (93.3%) compared to those with more severe invasion patterns, with similar survival rates across different postoperative therapies.
Article Synopsis
- * High-resolution imaging techniques allowed detailed evaluation of the absence, showing a dilated hemiazygos vein connecting to the left brachiocephalic vein.
- * This patient benefited from advanced imaging methods, which produced high-quality anatomical insights while reducing radiation exposure compared to standard CT scans.