The behavior of amidolytic factor VII in smoking and non-smoking pregnant women in relation to their gestational age.

Objective: Aim of the study was to assess the behavior of factor VII by commercial amidolytic assay in smoking and non-smoking pregnant women, and to compare this with the earlier reported factor VII:C levels during pregnancy and to discuss the role of F VII:Am with regard to thromboembolic complication in smoking pregnant women.

Methods: Blood samples were obtained for 75 non-smoking pregnant women and 109 smoking pregnant women. For the chromogenic determination of F VII:Am a COA-Set F VII test kit from Kabi Vitrum was used.

Haemostasis activation markers in plasma of patients with benign and malignant gynaecological tumours: a pilot study.

Coagulation and fibrinolysis activation have been investigated in fifty-eight women with recently detected gynaecological tumours. Twenty-six were benign and 32 malignant: of the last group nine patients had metastases. A control group consisted of 31 age-matched healthy women.

Fibrinogen and factor VII in male neonates.

Recent studies have suggested that retarded fetal and early growth predisposes to cardiovascular disease of males in adult life. This is partly explicable by an association between the haemostatic variables fibrinogen and factor VII and the placenta/birth weight ratio. Since many characteristics influence clotting factors during life, levels of fibrinogen and clotting factor VII were measured in cord blood of male neonates.

Cord blood clotting factors in neonates of smoking and non-smoking mothers.

Since smoking is known to influence hemostasis, the possible impact of maternal smoking on hemostatic variables in the newborn was studied. Cord blood clotting factors fibrinogen, factor VII, factor VIII:c and factor XIII were measured in 151 newborns. A significant reduction in birth weight and a rise in the placental/birth weight ratio was found in newborns of smoking mothers, which is in agreement with the literature.

Benign abdominal multicystic mesothelioma.

The benign abdominal multicystic mesothelioma is a rare disease. Usually a malignancy of the ovary is suspected prior to and during surgery. The histological diagnosis and the clinical course however are benign.