Publications by authors named "H M Rasmussen"

Background: FXYD3 is a Na/K-ATPase modulator which is upregulated in pancreatic ductal adenocarcinoma (PDAC), but its prognostic role is unknown. This study evaluated FXYD3 expression in chemo-naive patients with surgically-resected PDAC at a single centre (1993-2014).

Method: FXYD3 expression was assessed in tumour specimens using immunohistochemistry.

View Article and Find Full Text PDF

Introduction: Crohn's Disease (CD) is characterized by chronic intestinal inflammation and dysbiosis. This study aimed to investigate the effects of a plant-based diet (PBD) on gut microbiota composition and inflammation in CD patients and assess the utility of L gene sequencing for monitoring dietary adherence.

Methods: Fourteen CD patients participated in a 12-week PBD intervention.

View Article and Find Full Text PDF

Oxidative stress from placental ischemia/reperfusion and hypoxia/reoxygenation (H/R) in preeclampsia is accompanied by Na-K pump inhibition and S-glutathionylation of its β1 subunit (GSS-β1), a modification that inhibits the pump. β3-adrenergic receptor (β3-AR) agonists can reverse GSS-β1. We examined the effects of the agonist CL316,243 on GSS-β1 and sources of H/R-induced oxidative stress in immortalized first-trimester human trophoblast (HTR-8/SVneo) and freshly isolated placental explants from normal-term pregnancies.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted in Danish prisons to evaluate an initial on-site drug screening method and understand drug trends among inmates over two years.
  • The analysis involved urine samples from 710 inmates, testing for 123 substances using both on-site immunoassays and confirmatory lab methods, revealing high sensitivity and specificity in the screening process.
  • While the immunoassay was effective, it missed several significant drugs, leading to plans for a more comprehensive testing approach to reduce false negatives in detecting drug use.
View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to evaluate the wrist stabilizing effects and mechanical properties of four different materials used for wrist splints, including plaster of Paris (PoP), Woodcast, X-lite, and a 3D-printed polypropylene material.
  • - Using cadaveric arm specimens, researchers tested how well each splint material resisted wrist flexion and extension under a controlled load, and they also conducted a bending test on samples of each material.
  • - Results showed that PoP provided superior wrist stability and stiffness compared to the other materials, suggesting it may be the best option for wrist immobilization despite new alternatives like 3D printing.
View Article and Find Full Text PDF