Publications by authors named "H M Raslan"
Article Synopsis
- Knee osteoarthritis (KOA) is a major global disability issue, and the study aimed to explore the link between the ADAMTS14 gene polymorphism and KOA, along with associated risk factors.
- A case-control study involving 158 KOA patients and 120 matched controls showed a significant difference in ADAMTS14 gene rs4747096 allele frequencies, with certain genotypes (AA and AG) linked to increased KOA risk.
- Key risk factors identified include age over 50, obesity, prolonged standing at work, and the recessive inheritance pattern of the A allele, indicating a need for further research on the genetic influence on KOA development.
Background: Pulmonary hypertension "PH" is considered a serious cardiovascular disease. World Health Organization divided PH into groups depending on many factors like pathological, hemodynamic, and clinical pictures. Lately, various micro-RNAs "miRNAs" and other novel biomarkers like endoglin and asymmetric dimethylarginine "ADMA" might have a role in diagnosis of PH and may differentiate between pulmonary arterial hypertension "PAH" and non-PAH.
View Article and Find Full Text PDFOver 296 million people are estimated to have chronic hepatitis B viral infection (CHB), and it poses unique challenges for elimination. CHB is the result of hepatitis B virus (HBV)-specific immune tolerance and the presence of covalently closed circular DNA as mini chromosome inside the nucleus and the integrated HBV. Serum hepatitis B core-related antigen is the best surrogate marker for intrahepatic covalently closed circular DNA.
View Article and Find Full Text PDFAim: Assessing impact of lifestyle modification on Type 2 diabetes mellitus (T2DM) glycemic control and cognitive function.
Subjects & Methods: Prospective study was conducted on T2DM patients (92 patients as interventional group and 92 patients conventional therapy).
Results: After 6 months, significant improvements of HbA1c, oxidant and antioxidant, lipid profile, and cognitive function among only the interventional group (p < 0.
Vitamin D (VitD) and its receptor (VDR) have been intensively investigated in many cancers. As knowledge for head and neck cancer (HNC) is limited, we investigated the (pre)clinical and therapeutic relevance of the VDR/VitD-axis. We found that VDR was differentially expressed in HNC tumors, correlating to the patients' clinical parameters.
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