Publications by authors named "H M Nathoe"

Article Synopsis
  • A long-term study evaluated the outcomes of different heart procedures: on-pump CABG, off-pump CABG, and PCI over a 20-year period, using data from trials conducted between 1998 and 2000.
  • Findings showed no significant differences in overall mortality rates between on-pump and off-pump CABG or PCI and off-pump CABG.
  • However, off-pump CABG patients had fewer re-intervention procedures compared to those who underwent PCI.
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Background: Electronic informed consent (eIC) is increasingly used in clinical research due to several benefits including increased enrollment and improved efficiency. Within a learning health care system, a pilot was conducted with an eIC for linking data from electronic health records with national registries, general practitioners, and other hospitals.

Objective: We evaluated the eIC pilot by comparing the response to the eIC with the former traditional paper-based informed consent (IC).

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Background: Postoperative myocardial injury (PMI) comprises a spectrum of mechanisms resulting in troponin release. The impact of different PMI phenotypes on postoperative disability remains unknown.

Methods: This was a multicentre prospective cohort study including patients aged ≥50 yr undergoing elective major noncardiac surgery.

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Purpose: The Utrecht Cardiovascular Cohort-Second Manifestations of Arterial Disease (UCC-SMART) Study is an ongoing prospective single-centre cohort study with the aim to assess important determinants and the prognosis of cardiovascular disease progression. This article provides an update of the rationale, design, included patients, measurements and findings from the start in 1996 to date.

Participants: The UCC-SMART Study includes patients aged 18-90 years referred to the University Medical Center Utrecht, the Netherlands, for management of cardiovascular disease (CVD) or severe cardiovascular risk factors.

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Article Synopsis
  • * Researchers analyzed the data from 289 participants over a follow-up period of about 6.3 years, finding that the prevalence of CAC and the median CAC score increased significantly during this time.
  • * Results suggested that vigorous exercise intensity might reduce the increase in CAC scores, while very vigorous intensity exercise could actually lead to a greater increase in those scores, indicating a complex relationship between exercise intensity and coronary health.
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