Decoding β-catenin expression patterns in ovarian serous carcinoma with clinicopathological implications: insights from National Cancer Institute.

Aim: This study aimed to examine the immunohistochemical expression of β-catenin in serous ovarian carcinoma and to investigate its relationship with clinicopathological features and disease outcomes.

Methods: A retrospective analysis was conducted on 67 cases of serous ovarian carcinoma diagnosed at the Pathology Department of the Egyptian National Cancer Institute, Cairo University, between January 1, 2015, and December 31, 2017.

Results: The age of the patients ranged from 26 to 76 years.

A study of the role of androgen receptor and androgen receptor variant 7 in TNBC patients and the effect of their targeting by Enzalutamide and EPI-001 in MDA-MB-231.

The lack of targeted therapy for triple-negative breast cancer (TNBC) is among the mainsprings of its poor prognosis. This study aimed to elucidate the role of the androgen receptor (AR) and its splice variant 7 (ARv7) in TNBC patients. Further, the molecular impact of their blockers, Enzalutamide and EPI-001, on the TNBC cell line MDA-MB-231 was investigated.

The effect of water filter pitchers on the mineral concentration of tap water.

Objectives: To investigate the effect of water filter pitchers on the concentration of different minerals in tap water.

Methods: Nine water filter pitchers (A-I) were chosen based on consumer preferences and Amazon reviews. Each filter was tested for its ability to modify the concentrations of fluoride, calcium, magnesium, potassium, and sodium in tap water.

How periodic surfaces bend.

A periodic surface is one that is invariant by a two-dimensional lattice of translations. Deformation modes that stretch the lattice without stretching the surface are effective membrane modes. Deformation modes that bend the lattice without stretching the surface are effective bending modes.