Publications by authors named "H M Livingston"
Currently available biotherapeutics for the treatment of osteoporosis lack explicit mechanisms for bone localization, potentially limiting efficacy and inducing off-target toxicities. While various strategies have been explored for targeting the bone surface, critical aspects remain poorly understood, including the optimal affinity ligand, the role of binding avidity and circulation time, and, most importantly, whether or not this strategy can enhance the functional activity of clinically relevant protein therapeutics. To investigate, we generated fluorescent proteins (eg, mCherry) with site-specifically attached small molecule (bisphosphonate) or peptide (deca-aspartate, D10) affinity ligands.
View Article and Find Full Text PDFStudy Design: Systematic review and Meta-analysis.
Objective: This systematic review seeks to compare fusion, reoperation and complication rates, estimated blood loss (EBL), and surgical time between multi-level instrumented fusions with LIVs (lowest instrumented vertebra) in the cervical spine and those that extend into the thoracic spine.
Summary Of Background Data: Several studies address the question of whether to extend a long-segment, posterior cervical fusions, performed for degenerative disease, into the upper thoracic spine.
Objectives: Despite the efforts of various leading organizations in medical education, representation of black students in US medical schools has declined since the mid-1990s. The Florida State University College of Medicine (FSUCOM) has undertaken efforts to increase black and other underrepresented minority in medicine (URMM) representation in medical school through the Bridge to Clinical Medicine Program. This program is described and analyzed by the authors.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to find out what factors contribute to the success of students in medical school after completing a 1-year postbaccalaureate bridge program.
- In 2010, the researchers interviewed 15 graduates from The Florida State University College of Medicine Bridge program and analyzed the data, identifying 73 themes organized into 6 categories, including program attributes and personal qualities.
- The findings suggest that postbaccalaureate programs effectively prepare students for medical school, particularly those who may initially have less competitive academic credentials but show strong potential.