Publications by authors named "H M Linge"

Background And Aims: The enteric nervous system independently controls gastrointestinal function including motility, which is primarily mediated by the myenteric plexus, therefore also playing a crucial role in functional intestinal disorders. Live recordings from human myenteric neurons proved to be challenging due to technical difficulties. Using the neuroimaging technique, we are able to record human colonic myenteric neuronal activity and investigate their functional properties in a large cohort of patients.

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Gender-specific differences in hepatobiliary and transplantation surgery are decisive for the diagnosis, treatment and long-term outcomes. Men exhibit a higher risk of late recurrences and cancer-specific death after liver cancer resection. The emphasis on screening recommendations and ensuring equal access to treatment options are vital to minimize disparities.

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Article Synopsis
  • Radiation exposure to bone tissue in childhood cancer survivors is linked to an increased risk of bone cancer, with a stronger correlation observed for doses above 1 Gy.
  • A study of 228 cases and controls from 12 European countries found significant odds ratios for bone cancer related to radiation doses of 1-9 Gy and high cumulative doses of alkylating agents.
  • The findings highlight the need to revise clinical follow-up guidelines for childhood cancer survivors due to the increased risks, especially for specific chemotherapy drugs like procarbazine, ifosfamide, and cyclophosphamide.
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Adequate privacy protection is crucial for implementing modern AI algorithms in medicine. With Fully Homomorphic Encryption (FHE), a party without access to the secret key can perform calculations and advanced analytics on encrypted data without taking part of either the input data or the results. FHE can therefore work as an enabler for situations where computations are carried out by parties that are denied plain text access to sensitive data.

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The need for secure and integrity-preserved data sharing has become increasingly important in the emerging era of changed demands on healthcare and increased awareness of the potential of data. In this research plan, we describe our path to explore the optimal use of integrity preservation in health-related data contexts. Data sharing in these settings is poised to increase health, improve healthcare delivery, improve the offering of services and products from commercial entities, and strengthen healthcare governance, all with a maintained societal trust.

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