YibN, a bona fide interactor of the bacterial YidC insertase with effects on membrane protein insertion and membrane lipid production.

YidC, a prominent member of the Oxa1 superfamily, is essential for the biogenesis of the bacterial inner membrane, significantly influencing its protein composition and lipid organization. It interacts with the Sec translocon, aiding the proper folding of multi-pass membrane proteins. It also functions independently, serving as an insertase and lipid scramblase, augmenting the insertion of smaller membrane proteins while contributing to the organization of the bilayer.

A Comparative Analysis of Revision Rates in Surgical Treatments for Lumbar Isthmic Spondylolisthesis.

Study DesignRetrospective Cohort Study.ObjectiveIsthmic spondylolisthesis is frequently encountered in spine surgical practice, though there is a significant variation in surgical management strategies. We sought to evaluate revision rates between patients who underwent anterior-approach lumbar interbody fusion (ALIF) alone, posterolateral fusion (PLF) alone, PLIF/TLIF, and ALIF+PSF.

Detection of Genomic Copy Number Variations in Ovarian Cancer in the Peripheral Blood System.

Ovarian cancer has an incidence of 11 [...

A cohort study of prolactin and non-puerperal mastitis using real world data.

Non-puerperal mastitis (NPM) is an umbrella term for non-specific inflammatory mastitis that occurs during the non-puerperal period and has an unclear aetiology. The current study aims to characterize NPM patients and examine the determinants associated with NPM severity. This study analyzed the NPM inpatients admitted to the Department of Breast Surgery, Longhua Hospital Affiliated with the Shanghai University of Traditional Chinese Medicine from 2016 to 2020.

Rapid Authentication of Plant-Based Milk Alternatives by Coupling Portable Raman Spectroscopy with Machine Learning.

Background: Plant-based milk alternatives (PBMA) are increasingly popular due to rising lactose intolerance and environmental concerns over traditional dairy products. However, limited efforts have been made to develop rapid authentication methods to verify their biological origin.

Objective: In this study, we developed a rapid, on-site analytical method for the authentication and identification of PBMA made by six different plant species utilizing a portable Raman spectrometer coupled with machine learning.