Publications by authors named "H M Kadhim"
Angiogenesis is an intricate pathway that involves the formation of new blood capillaries from old, functioning ones. Improper angiogenesis is a feature of numerous maladies, including malignancy and autoimmune disorders. Indole-related derivatives are believed to interfere with the mitotic spindle, inhibiting the multiplication, and invasion of cancerous human cells.
View Article and Find Full Text PDFLiver fibrosis is a continuous wound-healing response to chronic injury caused by various chemical, virus, and pathological disorders; the lack of approved drugs or methods to reverse or prevent liver fibrosis makes it an interesting area of research. This study investigates the potential hepatoprotective effects of the phenolic extract of in rat's module of liver fibrosis. Liver fibrosis was induced by intraperitoneal injection of carbon tetrachloride (CCl) for six consecutive weeks; the butanol fraction of and silymarin was administered orally concurrently with CCl.
View Article and Find Full Text PDFBackground: In poultry, despite intense vaccination programs for prevention of Newcastle disease (ND), the ND infection still affects, causing high mortality in most vaccinated flocks.
Aim: This study aimed to determine whether the genetic material of the ND virus has changed and has become incompatible with the vaccines used in Iraq.
Methods: Real-time PCR was used to analyze genetic variation in the fusion (F) and haemaggluatination neuraminidase (HN) genes, as well as mRNA expression changes in inflammatory biomarkers, including C-reactive protein (CRP), interleukin 6, interleukin-1 beta (IL-6, IL-1β), and gamma interferon (IFN-γ).
Article Synopsis
- A study was conducted to assess the prevalence of a neglected bacterial pathogen in cattle in Iraq, aiming to identify its relationship with animal risk factors like age and sex through molecular assays and phylogenetic analysis.
- Out of 290 cattle tested, 7.24% were positive for the pathogen, with older animals showing significantly higher infection rates, while females had a marginally greater risk than males.
- The research successfully identified local bacterial strains that are closely related to strains found in France, marking the first molecular detection of this pathogen in Iraqi cattle and highlighting the need for further studies on its prevalence and control strategies.
Background: Drug-coated balloons (DCB) have promising results in the management of in-stent restenosis (ISR), still their role remains a major challenge, and not well established in contemporary clinical practice.
Aims: To provide a comprehensive appraisal of the efficacy and safety of DCBs in patients with in-stent restenosis (ISR).
Methods: We searched PubMed, Scopus, web of Science, Ovid, and Cochrane Central from inception until 30 March, 2023.